⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411 | 1.00 | — | — | |
| SCHEMBL8412 | 1.00 | — | — | |
| SCHEMBL10908419 | 0.94 | — | — | |
| SCHEMBL155027 | 0.94 | — | — | |
| SCHEMBL155028 | 0.94 | — | — | |
| SCHEMBL1705777 | 0.94 | — | — | |
| SCHEMBL18837574 | 0.88 | FAAH (0.32) | — | |
| SCHEMBL22553024 | 0.88 | — | — | |
| SCHEMBL22553025 | 0.88 | — | — | |
| SCHEMBL25181790 | 0.86 | FAAH (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2973 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032526-B1 | UNSATURATED ALKYL ESTERS OF 5-AMINOLEVULINIC ACID, THEIR PREPARATION AND THEIR USE | UNIV NAT CHONNAM IND FOUND (KR) | 2012-10-10 | — | — | EP | claimed |
| US-8198325-B2 | Unsaturated alkyl esters of 5-aminolevulinic acid, their preparation and their use | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2012-06-12 | — | — | US | claimed |
| EP-1479748-B1 | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-17 | — | — | EP | claimed |
| CN-100569716-C | Diphenyl acetylene derivatire and liquid crystal media | MERCK PATENT GMBH (DE) | 2009-12-16 | — | — | CN | claimed |
| US-20090176881-A1 | Unsaturated Alkyl Esters of 5-Aminolevulinic Acid, their Preparation and their Use | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2009-07-09 | — | — | US | claimed |
| EP-2032526-A1 | UNSATURATED ALKYL ESTERS OF 5-AMINOLEVULINIC ACID, THEIR PREPARATION AND THEIR USE | Industry Foundation of Chonnam National University (KR) | 2009-03-11 | — | — | EP | claimed |
| WO-2008002087-A1 | UNSATURATED ALKYL ESTERS OF 5-AMINOLEVULINIC ACID, THEIR PREPARATION AND THEIR USE | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2008-01-03 | — | — | WO | claimed |
| US-7255811-B2 | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | claimed |
| US-7052744-B2 | Liquid crystal mixtures having large values for the ratio between the elastic constants K33/K11 and relatevely small one for dielectric anisotropy and epsilon/epsilon bottom; broad d/p window; high long-term chemical stability and electrical resistance; low frequency and temperature dependence | MERCK PATENT GMBH (DE) | 2006-05-30 | — | — | US | claimed |
| US-7041347-B2 | 1,4-Di-(trans-4-cyclohexyl)benzene derivatives and their use in liquid crystal media and liquid crystal devices | MERCK PATENT GMBH (DE) | 2006-05-09 | — | — | US | claimed |
| CN-1572758-A | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2005-02-02 | — | — | CN | claimed |
| US-20040236138-A1 | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2004-11-25 | — | — | US | claimed |
| EP-0712918-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2002-06-12 | — | — | EP | claimed |
| EP-0167912-B1 | LIQUID CRYSTAL MIXTURES CONTAINING COMPOUNDS WITH A 4-ALKENYL OR 2Z-ALKENYL LATERAL CHAIN | F. HOFFMANN-LA ROCHE AG (CH) | 1990-01-03 | — | — | EP | claimed |
| US-4709030-A | 4-ALKENYL OR 2Z-ALKENYL POLYPHENYL COMPOUNDS; ELECTRO-OPTICS | HOFFMANN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | claimed |
| US-4621901-A | ELECTROOPTICS | HOFFMANN-LA ROCHE INC. (US) | 1986-11-11 | — | — | US | claimed |
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| CN-115677443-B | Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation | 中国科学院理化技术研究所 | 2024-07-16 | — | — | CN | disclosed |
| US-4709030-A | 4-ALKENYL OR 2Z-ALKENYL POLYPHENYL COMPOUNDS; ELECTRO-OPTICS | HOFFMANN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | disclosed |
| US-4621901-A | ELECTROOPTICS | HOFFMANN-LA ROCHE INC. (US) | 1986-11-11 | — | — | US | disclosed |