Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023333 | 1.00 | ALDH1A1 (0.33) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL5023297 | 0.88 | ALDH1A1 (0.35) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL3778037 | 0.88 | ALDH1A1 (0.35) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL1268514 | 0.86 | GAA (0.43) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL1268677 | 0.84 | MGAM (0.41) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL28479927 | 0.83 | MGAM (0.38) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL28479929 | 0.83 | MGAM (0.38) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL6469747 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL5138160 | 0.81 | ALDH1A1 (0.33) | ALDH1A1CYP3A4ALOX15TSHRTDP1 | |
| SCHEMBL27617039 | 0.80 | MGAM (0.38) | ALDH1A1CYP3A4ALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7420078-B2 | Process for the preparation of intermediates useful in the synthesis of statin derivatives especially 7-amino 3,5-dihydroxy heptanoic acid derivatives, and intermediates thereof | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-09-02 | — | — | US | claimed |
| EP-1404639-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF STATIN DERIVATIVES ESPECIALLY 7-AMINO 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, AND INTERMEDIATES THEREOF | Ciba SC Holding AG (CH) | 2004-04-07 | — | — | EP | claimed |
| WO-2003004450-A1 | PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF STATIN DERIVATIVES ESPECIALLY 7-AMINO 3,5-DIHYDROXY HEPTANOIC ACID DERIVATIVES, AND INTERMEDIATES THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-01-16 | — | — | WO | claimed |