Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 0.50 |
| ▸ | CHUK | O15111 | 6/20 | 0.50 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL551534 | 0.88 | IKBKB (0.67) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL14626810 | 0.85 | IKBKB (0.49) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL14627019 | 0.85 | IKBKB (0.61) | IKBKBCHUKBTKAURKAFLT3 | |
| Trifluoroacetic Acid SCHEMBL552022 | 0.84 | IKBKB (0.63) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL14627025 | 0.81 | IKBKB (0.53) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL552373 | 0.80 | IKBKB (0.63) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL5016911 | 0.80 | IKBKB (0.46) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL551536 | 0.79 | IKBKB (0.64) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL14019062 | 0.79 | IKBKB (0.59) | IKBKBCHUKBTKAURKAFLT3 | |
| SCHEMBL14018309 | 0.79 | IKBKB (0.68) | IKBKBCHUKBTKAURKAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896014-A2 | CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007005534-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-01-11 | — | — | WO | claimed |