Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383700 | 1.00 | FYN (0.32) | FYNKDM4EGAAELANEEPHX1 | |
| SCHEMBL1605475 | 1.00 | FYN (0.32) | FYNKDM4EGAAELANEEPHX1 | |
| SCHEMBL1385640 | 0.84 | SMN1; SMN2 (0.42) | FYNGAA | |
| SCHEMBL5450660 | 0.84 | SMN1; SMN2 (0.42) | FYNGAA | |
| SCHEMBL1384124 | 0.84 | SMN1; SMN2 (0.42) | FYNGAA | |
| SCHEMBL1386746 | 0.84 | SMN1; SMN2 (0.42) | FYNGAA | |
| Bromide SCHEMBL6389691 | 0.83 | SMN1; SMN2 (0.41) | FYNGAA | |
| SCHEMBL1605237 | 0.82 | ADORA1 (0.34) | FYN | |
| SCHEMBL1605232 | 0.82 | SLC29A1 (0.34) | FYNKDM4EGAAELANEEPHX1 | |
| SCHEMBL6426015 | 0.82 | AOC1 (0.31) | FYNKDM4EGAAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753736-B1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | AMGEN INC (US) | 2008-12-17 | — | — | EP | claimed |