SCHEMBL5023946

SCHEMBL5023946

CCO[Si](C)(c1ccccc1)c1ccccc1N

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADRA2B P18089 1/20 0.31
PTGS1 P23219 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242577 0.81 MAPT (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL63205 0.81 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL8038737 0.79 ESR1 (0.40) ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL5023590 0.79 TDP1 (0.39) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL818991 0.78 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL5024549 0.76 CYP3A4 (0.44) ALDH1A1TDP1CYP3A4CASP1SMN1; SMN2
SCHEMBL8505221 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL62857 0.76 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL28877020 0.75 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19
SCHEMBL18094252 0.72 ESR1 (0.33) ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240274848-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS COLORADO SCHOOL OF MINES 2024-08-15 US disclosed
WO-2022256669-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-08 WO disclosed
US-9240287-B2 Immobilized heteropoly acids and the use of the same electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2016-01-19 US disclosed
US-20140234750-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES (US) 2014-08-21 US disclosed
US-8753997-B2 Immobilized heteropoly acids and the use of the same for electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2014-06-17 US disclosed
US-20080299433-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES 2008-12-04 US disclosed