Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.75 |
| ▸ | PGR | P06401 | 9/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 3/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714037 | 1.00 | AR (0.75) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017775 | 1.00 | AR (0.75) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017844 | 0.88 | AR (0.68) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017880 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7879965 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6464801 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL24102494 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL24103286 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL1255845 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL14342101 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427748-B1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | ORGANON NV (NL) | 2008-05-14 | — | — | EP | disclosed |
| US-7169769-B2 | 17α-hydroxy-14β-steroids with hormonal effect | AKZO NOBEL N.V. (NL) | 2007-01-30 | — | — | US | disclosed |
| US-20040259849-A1 | 17Alpha-hydroxy-14Beta-steroids with hormonal effect | MERCK SHARP & DOHME B.V. (NL) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259849-A1 | 17Alpha-hydroxy-14Beta-steroids with hormonal effect | CYP17A1, HSD17B11, NR5A1 | AR 17/4885PGR 67/4885NR3C2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.