Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.75 |
| ▸ | PGR | P06401 | 9/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 3/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024779 | 1.00 | AR (0.75) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017775 | 1.00 | AR (0.75) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017844 | 0.88 | AR (0.68) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017880 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7879965 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6464801 | 0.86 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL24102494 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL24103286 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL1255845 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL14342101 | 0.86 | AR (1.00) | ARPGRNR3C2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427748-A1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | Akzo Nobel N.V. (NL) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003022864-A1 | 17ALPHA-HYDROXY-14BETA-STEROIDS WITH HORMONAL EFFECT | AKZO NOBEL N.V. (NL) | 2003-03-20 | — | — | WO | disclosed |