Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065423 | 0.93 | CYP2D6 (0.34) | LIPGCYP2D6ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5028543 | 0.82 | LIPG (0.36) | LIPGCYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL2811189 | 0.79 | CA1 (0.38) | CYP2D6ALDH1A1CYP1A2CYP2C19DRD2 | |
| SCHEMBL3681427 | 0.74 | LIPG (0.46) | LIPGALDH1A1SLC6A2HTR2AHTR2C | |
| SCHEMBL216968 | 0.74 | LIPG (0.46) | LIPGALDH1A1SLC6A2HTR2AHTR2C | |
| SCHEMBL218346 | 0.74 | LIPG (0.46) | LIPGALDH1A1SLC6A2HTR2AHTR2C | |
| SCHEMBL3684071 | 0.74 | LIPG (0.46) | LIPGALDH1A1SLC6A2HTR2AHTR2C | |
| SCHEMBL3685992 | 0.72 | LIPG (0.43) | LIPGALDH1A1SLC6A2HTR2CSLC6A4 | |
| Indene SCHEMBL22639000 | 0.69 | CYP2D6 (0.43) | LIPGCYP2D6ALDH1A1CYP1A2CYP2C19 | |
| Indene SCHEMBL20636898 | 0.68 | CA1 (0.44) | CYP2D6ALDH1A1CYP1A2CYP2C19SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916244-A1 | THIOPHENE COMPOUND HAVING SULFONYL GROUP AND PROCESS FOR PRODUCING THE SAME | Nissan Chemical Industries, Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |