Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606886 | 1.00 | MAPT (0.64) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL6139257 | 0.83 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL149167 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9823488 | 0.78 | MAPT (0.66) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL29666347 | 0.78 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL150552 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL9397206 | 0.76 | MAPT (0.79) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL1128303 | 0.76 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL1149940 | 0.76 | KMT2A (0.70) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL1150066 | 0.75 | MAPT (0.70) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |