Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653134 | 0.76 | MAPK1 (0.55) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL27583020 | 0.75 | MAPK1 (0.40) | MAPK1OGACCNE1CDK2CDK5 | |
| SCHEMBL25238058 | 0.74 | MAPK1 (0.56) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7666711 | 0.74 | MAPK1 (0.56) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL31202611 | 0.74 | MAPK1 (0.56) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL4651618 | 0.73 | MAPK1 (0.59) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10959901 | 0.72 | AOC3 (0.37) | MAPK1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5024045 | 0.72 | PSEN1 (0.39) | MAPK1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28685887 | 0.70 | CYP11B1 (0.53) | MAPK1ALDH1A1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL5024024 | 0.70 | PSEN1 (0.39) | MAPK1ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | MAPK1 3384/4885ALDH1A1 2222/4885MEN1 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.