SCHEMBL50257

SCHEMBL50257

C=Cc1ccccc1C(C)(C)C.C=Cc1ccccc1C(C)c1ccccc1C=C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALOX12 P18054 1/20 0.33
CA2 P00918 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11390245 0.90 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CA2
SCHEMBL27805 0.85 ALDH1A1 (0.50) ALDH1A1TSHRTDP1ALOX12CA2
SCHEMBL29801228 0.85 ALDH1A1 (0.50) ALDH1A1TSHRTDP1ALOX12CA2
SCHEMBL50011 0.85 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
SCHEMBL29364896 0.85 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CA2GABRA1
Benzene SCHEMBL11667348 0.83 ALDH1A1 (0.48) ALDH1A1TSHRTDP1ALOX12CA2
SCHEMBL5072506 0.83 ALDH1A1 (0.43) ALDH1A1TSHRCA2GABRA1GABRB2
Butadiene SCHEMBL28313891 0.81 ALDH1A1 (0.41) ALDH1A1TSHRGABRA1GABRB2
Butadiene SCHEMBL7155722 0.81 ALDH1A1 (0.46) ALDH1A1TSHRTDP1ALOX12CA2
Isopropylbenzene SCHEMBL27495315 0.79 ALDH1A1 (0.38) ALDH1A1TSHRTDP1ALOX12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129074-B2 Crosslinked nano-inorganic particle/polymer electrolyte membrane for membrane electrode assembly JAPAN ATOMIC ENERGY AGENCY (JP) 2012-03-06 US disclosed
US-20070207359-A1 Crosslinked nano-inorganic particle/polymer electrolyte membrane and method for producing same, and membrane electrode assembly using same JAPAN ATOMIC ENERGY AGENCY (JP) 2007-09-06 US disclosed