Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.35 |
| ▸ | FPR3 | P25089 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637058 | 0.92 | MAP2K7 (0.45) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1638394 | 0.91 | MAP2K7 (0.36) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1636814 | 0.90 | MAP2K7 (0.37) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| Hydrochloric Acid SCHEMBL1638286 | 0.89 | MAP2K7 (0.37) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL14277046 | 0.88 | MAP2K7 (0.36) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1636109 | 0.86 | JAK2 (0.39) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1638146 | 0.86 | CRHR1 (0.44) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1638332 | 0.85 | MAP2K7 (0.37) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL12534808 | 0.85 | CRHR1 (0.35) | MAP2K7CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1638253 | 0.84 | MAP2K7 (0.44) | MAP2K7CRHR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467997-B8 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-1467997-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-20 | — | — | EP | disclosed |
| WO-2004058767-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-15 | — | — | WO | disclosed |