Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5832697 | 0.98 | NOS3 (0.47) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL19271810 | 0.95 | NOS3 (0.43) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL868782 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL1954285 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL6088399 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL8031217 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL33526075 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL10427141 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL867932 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 | |
| SCHEMBL491780 | 0.93 | NOS3 (0.42) | NOS1NOS3DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953158-A1 | BICYCLIC CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-08-06 | — | — | EP | claimed |
| CN-118804917-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |