Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817581 | 0.80 | PPARG (0.56) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL1716121 | 0.80 | MAPK1 (0.53) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL10919969 | 0.80 | PPARG (0.56) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL29432927 | 0.78 | TDP1 (0.40) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL21096683 | 0.77 | KCNA3 (0.54) | MAPK1PKMTDP1LMNAALDH1A1 | |
| SCHEMBL1805351 | 0.77 | TDP1 (0.57) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL7363754 | 0.75 | PPARG (0.55) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL10815761 | 0.75 | TDP1 (0.55) | PKMPPARGPPARATDP1HPGD | |
| SCHEMBL13235836 | 0.75 | MTNR1A (0.53) | MAPK1PKMPPARGPPARATDP1 | |
| SCHEMBL8911823 | 0.75 | TDP1 (0.55) | MAPK1PKMPPARGPPARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983017-A1 | CURABLE COMPOSITION CONTAINING THIOL COMPOUND | Showa Denko K.K. (JP) | 2008-10-22 | — | — | EP | disclosed |