SCHEMBL5026249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5026253	0.95	KCNH2 (0.61)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5023606	0.92	KCNH2 (0.59)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5017506	0.91	KCNH2 (0.57)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5023799	0.90	KCNH2 (0.59)	KCNH2SLC6A9SLC6A3CACNA1FDRD4
	SCHEMBL5017462	0.89	SLC6A3 (0.54)	KCNH2SLC6A9SLC6A5SLC6A3CACNA1F
	SCHEMBL5024621	0.88	KCNH2 (0.73)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5023604	0.83	HTR2A (0.59)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5023698	0.81	CYP3A4 (0.57)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5027722	0.80	HTR2A (0.59)	KCNH2SLC6A3CACNA1FDRD4DRD5
	SCHEMBL5026290	0.79	CYP3A4 (0.57)	KCNH2SLC6A9SLC6A3CACNA1FDRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.