SCHEMBL5026892

SCHEMBL5026892

Cc1cccc2ccc(C(C)C)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.59
CYP2A6 P11509 5/20 0.59
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
HSD17B10 Q99714 2/20 0.53
LMNA P02545 1/20 0.45
TRPA1 O75762 1/20 0.44
PTGS1 P23219 1/20 0.44
CACNA1C Q13936 1/20 0.44
UGT2B7 P16662 1/20 0.42
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KIF11 P52732 1/20 0.38
CYP2D6 P10635 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KCNH2 Q12809 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598329 0.87 CYP1A2 (0.49) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL25547803 0.85 CYP1A2 (0.55) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL7927384 0.84 CYP1A2 (0.59) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL29191678 0.82 CYP1A2 (0.52) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL79573 0.80 UGT2B7 (0.42) CYP1A2CYP2A6ALDH1A1HPGDLMNA
SCHEMBL596870 0.79 CYP1A2 (0.49) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL31553088 0.79 CYP1A2 (0.49) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL29355679 0.79 CYP1A2 (0.49) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL28295455 0.79 ALDH1A1 (0.56) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL11468163 0.79 AKR1B1 (0.60) CYP1A2CYP2A6PTGS1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190224193-A1 Compositions of Natural Extracts and Use Thereof in Methods for Preventing or Treating Diseases REID CHRISTOPHER BRIAN (US) 2019-07-25 US claimed
WO-2017161387-A1 COMPOSITIONS OF NATURAL EXTRACTS AND USE THEREOF IN METHODS FOR PREVENTING OR TREATING DISEASES REID CHRISTOPHER BRIAN (US) 2017-09-21 WO claimed
US-20140271923-A1 Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions REID CHRISTOPHER BRIAN (US) 2014-09-18 US claimed
WO-2007066305-A1 COMPOSITIONS COMPRISING SESQUITERPENE COMPOUNDS FOR USE IN THE PROPHYLAXIS OR TREATMENT OF PAIN ZELPY 2549 (PTY) LIMITED (ZA) 2007-06-14 WO claimed
US-4408083-A SOLVENT EXTRACTION, THERMAL DECOMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-10-04 US claimed
US-20260048023-A1 LIPID NANOPARTICLE COMPRISING A DNA-BINDING PROTEIN SEQIRUS INC (US) 2026-02-19 US disclosed
EP-4572740-A1 LIPID NANOPARTICLE COMPRISING A DNA-BINDING PROTEIN Seqirus Inc. (US) 2025-06-25 EP disclosed
US-20240398941-A1 LIPID NANOPARTICLE COMPRISING A NUCLEIC ACID-BINDING PROTEIN Seqirus Inc. 2024-12-05 US disclosed
WO-2024209404-A1 RNA DELIVERY VEHICLE Seqirus Inc. (US) 2024-10-10 WO disclosed
EP-4412592-A1 LIPID NANOPARTICLE COMPRISING A NUCLEIC ACID-BINDING PROTEIN Seqirus Inc. (US) 2024-08-14 EP disclosed
WO-2024038407-A1 LIPID NANOPARTICLE COMPRISING A DNA-BINDING PROTEIN Seqirus Inc. (US) 2024-02-22 WO disclosed
WO-2023057935-A1 LIPID NANOPARTICLE COMPRISING A NUCLEIC ACID-BINDING PROTEIN Seqirus Inc. (US) 2023-04-13 WO disclosed
US-5639922-A CONTACTING AROMATIC PRIMARY AND TERTIARY HYDROPEROXIDES MIXTURE OBTAINED BY OXIDATION OF ALKYLAROMATIC COMPOUNDS WITH AN ALKALI OR ALKALINE ORGANIC AROMATIC CARBOXYLIC ACID SALT, DECOMPOSING WITH ACID CATALYST FORMING ALKYL PHENOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed
CN-1128754-A Method for treatment of mixture of hydroperoxide SUMITOMO CHEMICAL CO (JP) 1996-08-14 CN disclosed
US-5166451-A Peroxide mixture and quaternary ammonium salt for reducing the content of primary hydroperoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-24 US disclosed
CN-1009927-B Treatment of hydroperoxide mixtures SUMITOMO CHEMICAL CO (JP) 1990-10-10 CN disclosed
CN-87105264-A The processing of hydroperoxide mixture 1988-05-18 CN disclosed
EP-0046405-B1 METHOD OF TREATING HYDROPEROXIDE MIXTURES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-07-11 EP disclosed
US-4408083-A SOLVENT EXTRACTION, THERMAL DECOMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-10-04 US disclosed
EP-0046405-A1 Method of treating hydroperoxide mixtures MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048023-A1 LIPID NANOPARTICLE COMPRISING A DNA-BINDING PROTEIN SREBF1, SREBF2, CNBP CYP1A2 4861/4885CYP2A6 4772/4885ALDH1A1 4631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.