Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19053037 | 0.81 | PDPK1 (0.34) | PDPK1YTHDC1YTHDF2MAP4K4 | |
| SCHEMBL12636376 | 0.79 | PDE4A (0.34) | HTT | |
| SCHEMBL5031544 | 0.74 | CYP3A4 (0.42) | MAPTKDM4ELMNAHTTKMT2A | |
| SCHEMBL13081887 | 0.74 | — | — | |
| SCHEMBL14782611 | 0.73 | PDPK1 (0.39) | PDPK1YTHDC1YTHDF2MAP4K4MAPT | |
| SCHEMBL14123472 | 0.71 | YTHDC1 (0.41) | PDPK1YTHDC1YTHDF2MAP4K4LMNA | |
| SCHEMBL14010082 | 0.71 | PDPK1 (0.38) | PDPK1YTHDC1YTHDF2MAP4K4KDM4E | |
| SCHEMBL5031499 | 0.71 | EGFR (0.50) | LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1440229 | 0.69 | PDPK1 (0.37) | PDPK1YTHDC1YTHDF2MAP4K4LMNA | |
| SCHEMBL766829 | 0.69 | GALR3 (0.49) | PDPK1YTHDC1YTHDF2RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |