Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027098 | 1.00 | MAPT (0.48) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL15047063 | 0.84 | MEN1 (0.47) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL4115529 | 0.82 | MAPT (0.63) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL4115527 | 0.82 | MAPT (0.63) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL6710803 | 0.81 | MAPT (0.50) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL5442765 | 0.81 | MEN1 (0.47) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL5442763 | 0.81 | MEN1 (0.47) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL8357961 | 0.81 | MEN1 (0.47) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL2174834 | 0.79 | CA2 (0.54) | MAPTSMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL2174838 | 0.79 | CA2 (0.54) | MAPTSMN1; SMN2LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935874-A1 | S1P3 RECEPTOR ANTAGONIST | TOA EIYO LTD. (JP) | 2008-06-25 | — | — | EP | disclosed |