Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031120 | 0.95 | HSD11B1 (0.43) | HSD11B1L3MBTL1ALDH1A1DPP9DPP7 | |
| SCHEMBL5031162 | 0.93 | HSD11B1 (0.45) | HSD11B1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10129621 | 0.86 | MEN1 (0.46) | HSD11B1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL496002 | 0.84 | MEN1 (0.44) | HSD11B1L3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15076636 | 0.81 | DPP9 (0.36) | DPP9DPP7 | |
| SCHEMBL21880359 | 0.81 | DPP9 (0.36) | DPP9DPP7MEN1KMT2A | |
| SCHEMBL15076715 | 0.79 | DPP9 (0.50) | HSD11B1DPP9DPP7 | |
| SCHEMBL5031123 | 0.79 | GAA (0.50) | L3MBTL1ALDH1A1DPP9DPP7SMN1; SMN2 | |
| SCHEMBL20163985 | 0.79 | DPP7 (0.37) | DPP9DPP7 | |
| SCHEMBL13321795 | 0.79 | HSD11B1 (0.48) | HSD11B1DPP9DPP7LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429609-B2 | Pyrazole compound and medicinal composition containing the same | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| EP-1510516-A1 | PYRAZOLE COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |