SCHEMBL502824

SCHEMBL502824

Cc1nc(F)ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578026 0.74
SCHEMBL30491083 0.74
SCHEMBL31452225 0.74
SCHEMBL6912131 0.74
SCHEMBL17285647 0.74
SCHEMBL25292508 0.74
SCHEMBL9157488 0.74
SCHEMBL156190 0.74
SCHEMBL18318562 0.73 CCR1 (0.34)
Hydrochloric Acid SCHEMBL6604967 0.72 RAB9A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102898358-A Preparation method of fluoropyridine compounds SHANGHAI TITAN TECHNOLOGY CO LTD 2013-01-30 CN claimed
CN-119707952-B Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN disclosed
US-20260132140-A1 IMIDAZOLYL-AMINO-PYRAZINE-CARBONITRILS AS CHK-1 INHIBITORS BENEVOLENTAI BIO LTD (GB) 2026-05-14 US disclosed
EP-4720071-A1 COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE Beone Medicines I GmbH (CH) 2026-04-08 EP disclosed
EP-4676927-A1 HETEROCYCLIC COMPOUNDS AS WRN INHIBITORS Synnovation Therapeutics, Inc. (US) 2026-01-14 EP disclosed
US-20250346609-A1 COT MODULATORS AND METHODS OF USE THEREOF GILEAD SCIENCES INC (US) 2025-11-13 US disclosed
EP-4626864-A1 LINEAR HETEROARYL DIAMIDE IRE1/XBP1S ACTIVATORS Protego Biopharma, Inc. (US) 2025-10-08 EP disclosed
EP-4620955-A1 MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2025-09-24 EP disclosed
US-12421228-B2 Naphthyridine derivatives as PRC2 inhibitors Mirati Therapeutics, Inc. (US) 2025-09-23 US disclosed
US-20250282787-A1 SUBSTITUTED IMIDAZO[1,2-c]PYRIMIDINES AS PRC2 INHIBITORS Mirati Therapeutics, Inc. 2025-09-11 US disclosed
EP-2114935-B1 PIPERIDINE GPCR AGONISTS PROSIDION LTD (GB) 2011-07-20 EP disclosed
CN-102083813-A Piperidinyl gpcr agonists PROSIDION LTD 2011-06-01 CN disclosed
EP-2254892-A1 BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES Global Alliance For Tb Drug Development (US) 2010-12-01 EP disclosed
US-20100105732-A1 PIPERIDINE GPCR AGONISTS PROSIDION LIMITED (GB) 2010-04-29 US disclosed
US-7666864-B2 Bicyclic nitroimidazole-substituted phenyl oxazolidinones GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2010-02-23 US disclosed
WO-2010004345-A1 PIPERIDINYL GPCR AGONISTS PROSIDION LIMITED (GB) 2010-01-14 WO disclosed
US-20090281088-A1 BICYCLIC NITROIMIDAZOLE-SUBSTITUTED PHENYL OXAZOLIDINONES GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2009-11-12 US disclosed
EP-2114935-A1 PIPERIDINE GPCR AGONISTS Prosidion Limited (GB) 2009-11-11 EP disclosed
WO-2009120789-A1 BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2009-10-01 WO disclosed
WO-2008081207-A1 PIPERIDINE GPCR AGONISTS PROSIDION LIMITED (GB) 2008-07-10 WO disclosed