Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | ANTXR2 | P58335 | 3/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652344 | 0.98 | NT5E (0.53) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL3700974 | 0.94 | ANTXR2 (0.50) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL10148750 | 0.93 | PTPN1 (0.58) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL21148453 | 0.93 | PTPN1 (0.58) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL27988766 | 0.92 | NT5E (0.49) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL3652342 | 0.92 | NT5E (0.49) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL19885159 | 0.90 | NT5E (0.49) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL20411238 | 0.89 | NT5E (0.49) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL12920559 | 0.89 | FGF1 (0.46) | PTPN1NT5EKMT2AUSP2MEN1 | |
| SCHEMBL12154605 | 0.87 | PTPN1 (0.68) | PTPN1NT5EKMT2AUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| EP-1999124-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007098597-A1 | GLYCOSIDASE INHIBITORS AND METHODS OF SYNTHESIZING SAME | SIMON FRASER UNIVERSITY (CA) | 2007-09-07 | — | — | WO | disclosed |