SCHEMBL5028458

SCHEMBL5028458

Nc1c(-c2cccc3ccccc23)cccc1-c1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 3/20 0.54
TSHR P16473 2/20 0.54
HPGD P15428 2/20 0.54
KEAP1 Q14145 2/20 0.54
CYP3A4 P08684 1/20 0.54
DHFR P00374 1/20 0.47
CYP2A6 P11509 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
ALOX15 P16050 1/20 0.43
PTPN1 P18031 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
CYP1A2 P05177 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4943495 0.93 ALDH1A1 (0.52) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL1718300 0.89 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL24432943 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL30843336 0.89 ALDH1A1 (0.48) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL1225129 0.89 ALDH1A1 (0.60) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL4922374 0.88 ALDH1A1 (0.45) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL28613236 0.87 ALDH1A1 (0.46) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL29177949 0.87 ALDH1A1 (0.58) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL1809982 0.87 ALDH1A1 (0.58) ALDH1A1HSD17B10TSHRHPGDKEAP1
SCHEMBL25302086 0.87 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRHPGDKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2453496-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE Konica Minolta Holdings, Inc. (JP) 2012-05-16 EP disclosed
EP-2395573-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT Konica Minolta Holdings, Inc. (JP) 2011-12-14 EP disclosed