Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PER2 | O15055 | 1/20 | 0.50 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.50 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607881 | 0.84 | LMNA (1.00) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL607488 | 0.83 | LMNA (0.82) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL608283 | 0.82 | LMNA (0.81) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL608025 | 0.82 | LMNA (0.72) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL609395 | 0.81 | LMNA (0.75) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL607474 | 0.81 | LMNA (1.00) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL6815269 | 0.80 | POLB (0.84) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL609435 | 0.79 | LMNA (0.75) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL606435 | 0.77 | LMNA (0.80) | LMNAGAAHTTMAPK1MAPT | |
| SCHEMBL16066039 | 0.77 | PTGDR2 (0.64) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |