Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | PER2 | O15055 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609875 | 0.88 | CNR2 (0.45) | RAD52NLRP1PER2ALDH1A1LMNA | |
| SCHEMBL5024381 | 0.81 | RAD52 (0.47) | RAD52NLRP1PER2ALDH1A1LMNA | |
| SCHEMBL5025290 | 0.80 | RAD52 (0.58) | RAD52NLRP1ALDH1A1LMNAMEN1 | |
| SCHEMBL609624 | 0.77 | RAD52 (0.51) | RAD52NLRP1PER2ALDH1A1LMNA | |
| SCHEMBL5025336 | 0.75 | MEN1 (0.60) | RAD52ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5025287 | 0.74 | MEN1 (0.62) | RAD52ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5022677 | 0.74 | MEN1 (0.62) | RAD52ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5025317 | 0.74 | MEN1 (0.62) | RAD52ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL606776 | 0.71 | RAD52 (0.57) | RAD52NLRP1PER2ALDH1A1LMNA | |
| SCHEMBL6816191 | 0.70 | RAD52 (0.76) | RAD52NLRP1ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-B1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | SERONO LAB (CH) | 2008-06-04 | — | — | EP | claimed |