Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029319 | 0.87 | — | — | |
| SCHEMBL1811527 | 0.77 | BTK (0.37) | BTKEPHX1PKMKDM1A | |
| SCHEMBL5029532 | 0.75 | CCR2 (0.34) | — | |
| SCHEMBL5029481 | 0.74 | EPHX1 (0.34) | TRPM8BTKEPHX1PKMKDM1A | |
| SCHEMBL5029474 | 0.74 | EPHX1 (0.34) | TRPM8BTKEPHX1PKMKDM1A | |
| SCHEMBL1700015 | 0.73 | EPHX1 (0.40) | EPHX1PKM | |
| SCHEMBL5033649 | 0.72 | CCR2 (0.34) | — | |
| SCHEMBL20549583 | 0.70 | BTK (0.45) | BTKEPHX1 | |
| SCHEMBL1192724 | 0.70 | EPHX1 (0.33) | BTKEPHX1KDM1A | |
| SCHEMBL15970550 | 0.68 | POLB (0.41) | BTKEPHX1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378409-B2 | Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |