SCHEMBL5029752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5030830	0.95	IL2 (0.42)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL5030860	0.89	IL2 (0.48)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL5032084	0.89	IL2 (0.39)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL5030853	0.88	IL2 (0.50)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL13640688	0.87	IL2 (0.42)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL5027253	0.86	IL2 (0.45)	IL2STIM1ORAI1ALDH1A1ABL1
	SCHEMBL5033973	0.85	IL2 (0.42)	IL2STIM1ORAI1ORAI2ALDH1A1
	SCHEMBL5436399	0.85	ABCB1 (0.39)	IL2ABL1NPC1RAB9AABCB1
	SCHEMBL14360779	0.80	NPC1 (0.34)	IL2ABL1NPC1RAB9AABCB1
	SCHEMBL8227365	0.79	ABCB1 (0.38)	IL2STIM1ORAI1ALDH1A1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.