SCHEMBL5030331

SCHEMBL5030331

Cc1ccc(C(CC(=O)O)NC(=O)c2ccco2)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
CYP26A1 O43174 2/20 0.57
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 2/20 0.51
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TP53 P04637 1/20 0.51
CTSA P10619 5/20 0.48
MAPT P10636 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030328 1.00 KMT2A (0.61) KMT2ACYP26A1ALDH1A1KDM4ERAB9A
SCHEMBL4277594 0.89 ALDH1A1 (0.66) KMT2ACYP26A1ALDH1A1KDM4ERAB9A
SCHEMBL4277587 0.89 ALDH1A1 (0.66) KMT2ACYP26A1ALDH1A1KDM4ERAB9A
SCHEMBL3519639 0.87 KMT2A (0.58) KMT2ACYP26A1ALDH1A1RAB9ANPC1
SCHEMBL13401725 0.86 KMT2A (0.67) KMT2AALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL1138655 0.85 KMT2A (0.54) KMT2AALDH1A1KDM4ERAB9ANPC1
SCHEMBL1138653 0.85 KMT2A (0.54) KMT2AALDH1A1KDM4ERAB9ANPC1
SCHEMBL5720879 0.82 KMT2A (0.49) KMT2ACYP26A1ALDH1A1KDM4ERAB9A
SCHEMBL3517840 0.81 KMT2A (0.86) KMT2AALDH1A1RAB9ASMN1; SMN2MAPT
SCHEMBL5720956 0.81 KMT2A (0.50) KMT2AALDH1A1KDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080038785-A1 Processes For Preparing Optically Active (S Or R-)-Beta-Amino Acid And Optically Active (R Or S)-Beta-Amino Acid Ester, And Beta-Amino Acid 2-Alkoxyethyl Ester And Optically Active (S Or R)-Beta Amino Acid 2-Alkoxyethyl Ester UBE INDUSTRIES, LTD. (JP) 2008-02-14 US disclosed
EP-1840218-A1 PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)- BETA-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-BETA -AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF -AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF -AMINO ACIDS Ube Industries, Ltd. (JP) 2007-10-03 EP disclosed