SCHEMBL50304

SCHEMBL50304

CCC(C)=CCc1c(OC)ccc2ccc(=O)oc12

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 3/20 0.79
▸ ALDH1A1 P00352 2/20 0.79
▸ XPO1 O14980 1/20 0.79
▸ ABCB1 P08183 1/20 0.79
▸ CYP3A4 P08684 1/20 0.79
▸ ALOX5 P09917 1/20 0.79
▸ GABRA1 P14867 1/20 0.79
▸ GABRB2 P47870 1/20 0.79
▸ KDM4E B2RXH2 3/20 0.66
▸ HPGD P15428 1/20 0.66
▸ MCL1 Q07820 1/20 0.56
▸ CA9 Q16790 5/20 0.55
▸ SRD5A1 P18405 2/20 0.54
▸ PDE4D Q08499 1/20 0.54
▸ MAOA P21397 1/20 0.53
▸ PTGS1 P23219 1/20 0.53
▸ LMNA P02545 1/20 0.50
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA7 P43166 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50303 1.00 PTGS2 (0.79) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL50436 0.88 PTGS2 (1.00) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL29595542 0.88 PTGS2 (1.00) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL17513161 0.88 PTGS2 (1.00) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL27803504 0.87 PTGS2 (0.92) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL27950752 0.87 PTGS2 (0.97) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL27681201 0.87 PTGS2 (0.97) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL27659943 0.84 PTGS2 (0.90) PTGS2ALDH1A1XPO1ABCB1CYP3A4
SCHEMBL27890626 0.80 KDM4E (0.71) PTGS2ALDH1A1XPO1ABCB1CYP3A4
Osthole SCHEMBL28851790 0.80 PTGS2 (0.82) PTGS2ALDH1A1XPO1ABCB1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230041289-A1 COMPOSITIONS AND METHODS FOR ENHANCING OR TREATING FEMALE SEXUAL RESPONSE T K INC APS (DK) 2023-02-09 — — US disclosed
US-9968632-B2 Fast acting joint relief formulations NATURES PRODUCTS, INC. (US) 2018-05-15 — — US disclosed
US-9956310-B2 Time indicator tampon MARTELLO, JOHN J. 2018-05-01 — — US disclosed
US-20180055874-A1 FAST ACTING JOINT RELIEF FORMULATIONS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2018-03-01 — — US disclosed
US-9808483-B2 Fast acting joint relief formulations NATURES PRODUCTS, INC. (US) 2017-11-07 — — US disclosed
CN-107163013-A A kind of method that Osthole is prepared from plant and the application in cosmetics are prepared 广州市娇兰化妆品有限公司 2017-09-15 — — CN disclosed
US-20170049804-A1 FAST ACTING JOINT RELIEF FORMULATIONS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2017-02-23 — — US disclosed
US-9486476-B2 Fast acting joint relief formulations Natures Products, Inc (US) 2016-11-08 — — US disclosed
US-20160038531-A1 FAST ACTING JOINT RELIEF FORMULATIONS JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-11 — — US disclosed
US-20150217019-A1 TIME INDICATOR TAMPON MARTELLO, JOHN J 2015-08-06 — — US disclosed
WO-2014015192-A1 TIME INDICATOR TAMPON MARTELLO JEANNETTE (US) 2014-01-23 — — WO disclosed
US-8128972-B2 Compositions and methods for enhancing and treating female sexual response SEMPRAE LABORATORIES, INC. (US) 2012-03-06 — — US disclosed
US-20110117228-A1 COMPOSITIONS AND METHODS FOR ENHANCING AND TREATING FEMALE SEXUAL RESPONSE SEMPRAE LABORATORIES, INC. 2011-05-19 — — US disclosed
US-7875299-B2 Borage seed oil and angelica pubescens root; topical SEMPRAE LABORATORIES, INC. (US) 2011-01-25 — — US disclosed
EP-1328281-B1 COMPOSITIONS AND METHODS FOR TREATING FEMALES SEXUAL RESPONSE QUALILIFE PHARMACEUTICALS INC (US) 2007-08-15 — — EP disclosed
US-20040202739-A1 Compositions and methods for treating female sexual response SEMPRAE LABORATORIES, INC. 2004-10-14 — — US disclosed
US-6737084-B2 Compositions and methods for enhancing or treating female sexual response QUALILIFE 2004-05-18 — — US disclosed
EP-1328281-A1 COMPOSITIONS AND METHODS FOR TREATING FEMALES SEXUAL RESPONSE Qualilife Pharmaceuticals Inc. (US) 2003-07-23 — — EP disclosed
US-20020034557-A1 Compositions and methods for treating female sexual response SEMPRAE LABORATORIES, INC. 2002-03-21 — — US disclosed
WO-2002000240-A2 COMPOSITIONS AND METHODS FOR TREATING FEMALES SEXUAL RESPONSE QUALILIFE PHARMACEUTICALS INC. (US) 2002-01-03 — — WO disclosed
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