Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762350 | 0.80 | PRSS1 (0.96) | PRSS1PRSS2PRSS3TSHRCES2 | |
| Hydrochloric Acid SCHEMBL1262882 | 0.79 | PRSS1 (1.00) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL894417 | 0.75 | TSHR (1.00) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL29848105 | 0.75 | TSHR (1.00) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL18518479 | 0.75 | TSHR (0.58) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL8629297 | 0.74 | TSHR (0.67) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL8629294 | 0.74 | TSHR (0.67) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL8629293 | 0.74 | TSHR (0.67) | PRSS1PRSS2PRSS3TSHRCES2 | |
| Guanidine SCHEMBL28122612 | 0.74 | PRSS1 (0.67) | PRSS1PRSS2PRSS3TSHRCES2 | |
| SCHEMBL2308208 | 0.74 | TSHR (0.71) | PRSS1PRSS2PRSS3TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453496-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, NOVEL COMPOUND, LIGHTING DEVICE AND DISPLAY DEVICE | Konica Minolta Holdings, Inc. (JP) | 2012-05-16 | — | — | EP | disclosed |