Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | CES2 | O00748 | 1/20 | 0.72 |
| ▸ | CES1 | P23141 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848105 | 1.00 | TSHR (1.00) | TSHRCES2CES1TP53PRSS1 | |
| Methane SCHEMBL28159024 | 0.98 | TSHR (0.96) | TSHRCES2CES1TP53PRSS1 | |
| Hydrochloric Acid SCHEMBL7389430 | 0.98 | TSHR (0.96) | TSHRCES2CES1TP53PRSS1 | |
| Isobutane SCHEMBL6119723 | 0.93 | TSHR (0.87) | TSHRCES2CES1TP53PRSS1 | |
| SCHEMBL28245589 | 0.90 | TSHR (0.81) | TSHRCES2CES1TP53PRSS1 | |
| Dinitrophenylene SCHEMBL27446197 | 0.88 | TSHR (0.78) | TSHRCES2CES1TP53PRSS1 | |
| SCHEMBL15054453 | 0.85 | TSHR (0.73) | TSHRCES2CES1TP53PRSS1 | |
| SCHEMBL10792177 | 0.85 | CES2 (0.79) | TSHRCES2CES1TP53PRSS1 | |
| SCHEMBL23079050 | 0.85 | TSHR (0.73) | TSHRCES2CES1TP53PRSS1 | |
| SCHEMBL195692 | 0.85 | TSHR (0.73) | TSHRCES2CES1TP53PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025131978-A1 | DRUG-LINKER REAGENTS FOR CONJUGATION | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-06-26 | — | — | WO | claimed |
| CN-119371298-A | Method for efficiently synthesizing indenone compound | 南阳师范学院 | 2025-01-28 | — | — | CN | claimed |
| CN-111018720-B | Method for preparing m-phenylenediamine | 上海交通大学 | 2021-01-22 | — | — | CN | claimed |
| CN-111018720-A | Method for preparing m-phenylenediamine | 上海交通大学 | 2020-04-17 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2017-10-05 | — | — | US | claimed |
| EP-3187486-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | Amorepacific Corporation (KR) | 2017-07-05 | — | — | EP | claimed |
| CN-102105437-B | Adamantyl diamide derivatives and uses of same | LUNDBECK & CO AS H | 2014-07-23 | — | — | CN | claimed |
| CN-103221384-A | Benzamide derivative with anticancer activity and preparation method and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2013-07-24 | — | — | CN | claimed |
| CN-103097352-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2013-05-08 | — | — | CN | claimed |
| CN-1202888-A | Isoquinoline derivatives and isoquinoline combinatorial libraries | TORREY PINES INST (US) | 1998-12-23 | — | — | CN | claimed |
| WO-1998051307-A1 | METHODS FOR TREATING INFLAMMATION, INFLAMMATORY DISEASES, ARTHRITIS AND STROKE USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | claimed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | claimed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | claimed |
| US-5468585-A | Resin composition for use in an electrophotographic toner | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-11-21 | — | — | US | claimed |
| WO-1995020637-A2 | HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS | MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) | 1995-08-03 | — | — | WO | claimed |
| EP-0662641-A1 | Resin composition for electrophotographic tone | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-07-12 | — | — | EP | claimed |
| EP-0345551-B1 | EASILY FLOWABLE DELAYED CRYSTALLISING POLYARYLENE SULFIDE-MIXTURES | BAYER AG (DE) | 1993-09-08 | — | — | EP | claimed |
| EP-0275221-B1 | N-(1H-INDOL-4-YL) BENZAMIDE DERIVATIVES, THEIR SALTS AND THEIR USE AS MEDICINES, AND COMPOSITION CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-04-17 | — | — | EP | claimed |
| EP-0275221-A2 | N-(1H-indol-4-yl) benzamide derivatives, their salts and their use as medicines, and composition containing them | ROUSSEL-UCLAF (FR) | 1988-07-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283347-A1 | NOVEL ADAMANTANE DERIVATIVE COMPOUND | ADAM8, CYP17A1, ADAM10 | TSHR 3845/4885CES2 1095/4885CES1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.