SCHEMBL5031041

SCHEMBL5031041

CC[Si](OC1CCCCC1)(OC1CCCCC1)OC1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
NAAA Q02083 2/20 0.33
SHBG P04278 1/20 0.32
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
ACHE P22303 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551412 0.81 EPHX1 (0.38) EPHX1NAAASHBGCYP1A2
SCHEMBL21248072 0.80 EPHX1 (0.36) EPHX1NAAASHBGADH1CADH1A
SCHEMBL27104105 0.80 EPHX1 (0.36) EPHX1NAAASHBGADH1CADH1A
SCHEMBL5031013 0.78 NAAA (0.41) EPHX1NAAACYP1A2
Methylamine SCHEMBL2251740 0.78 EPHX1 (0.36) EPHX1NAAACYP1A2CA1CA2
SCHEMBL29050162 0.77 EPHX1 (0.33) EPHX1NAAA
SCHEMBL301545 0.77 EPHX1 (0.38) EPHX1NAAA
SCHEMBL11414892 0.76 EPHX1 (0.34) EPHX1NAAASHBG
SCHEMBL5031089 0.76 NAAA (0.43) EPHX1NAAACYP1A2
SCHEMBL5029803 0.75 CYP19A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed