Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032369 | 0.96 | LMNA (0.37) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL11394822 | 0.81 | MAPT (0.38) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL3898315 | 0.80 | LMNA (0.34) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL5027484 | 0.79 | CA4 (0.39) | LMNAALDH1A1LTA4HL3MBTL1MAOA | |
| SCHEMBL20513805 | 0.78 | MAPT (0.33) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL20513946 | 0.78 | MAPT (0.33) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL20513711 | 0.78 | MAPT (0.33) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL20513402 | 0.78 | MAPT (0.33) | LMNAALDH1A1MAPTGPBAR1CYSLTR1 | |
| SCHEMBL5029901 | 0.75 | CA4 (0.39) | LMNAALDH1A1LTA4HL3MBTL1MAOA | |
| SCHEMBL5032307 | 0.75 | CA4 (0.39) | LMNAALDH1A1LTA4HL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |