Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31536924 | 1.00 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL692713 | 1.00 | HTR2A (0.40) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL9145024 | 0.98 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL9145029 | 0.98 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL9146505 | 0.98 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| Lithium SCHEMBL9146515 | 0.98 | HTR2A (0.39) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL4652369 | 0.82 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL14802891 | 0.82 | HTR2A (0.38) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL8088750 | 0.82 | HTR2A (0.42) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL9143221 | 0.80 | HTR2A (0.36) | HTR2AHTR6SIGMAR1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | B2M, CDYL, MLX | HTR2A 3034/4885HTR6 4134/4885SIGMAR1 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.