Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031407 | 1.00 | CTSC (0.46) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL6513822 | 0.82 | CTSC (0.44) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL1308857 | 0.82 | CTSC (0.44) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL1308859 | 0.82 | CTSC (0.44) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL9539351 | 0.81 | SLC7A5 (0.46) | SLC7A5TAAR1SLC6A2CYP1A2 | |
| SCHEMBL9539354 | 0.81 | SLC7A5 (0.46) | SLC7A5TAAR1SLC6A2CYP1A2 | |
| SCHEMBL8776735 | 0.80 | CTSC (0.42) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL1529264 | 0.80 | CTSC (0.46) | CTSCEPHX1ALPIPKMPTGS1 | |
| SCHEMBL6852331 | 0.80 | TAAR1 (0.53) | CTSCTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL1310109 | 0.80 | TAAR1 (0.53) | CTSCTAAR1SLC6A2MAOASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996183-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007106938-A1 | METHOD OF TREATMENT OR PROPHYLAXIS INFLAMMATORY PAIN | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-09-27 | — | — | WO | disclosed |
| EP-1830869-A1 | METHOD OF TREATMENT OR PROPHYLAXIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066361-A1 | METHOD OF TREATMENT OR PROPHYLAXIS | THE UNIVERSITY OF QUEENSLAND (AU) | 2006-06-29 | — | — | WO | disclosed |
| EP-0393445-A2 | Use of peptide renin inhibitors as an agent against retrovirus | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4837305-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-06-06 | — | — | US | disclosed |
| US-4687873-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-08-18 | — | — | US | disclosed |