Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776731 | 1.00 | CTSC (0.42) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 | |
| SCHEMBL1308859 | 0.82 | CTSC (0.44) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 | |
| SCHEMBL1308857 | 0.82 | CTSC (0.44) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 | |
| SCHEMBL6513822 | 0.82 | CTSC (0.44) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 | |
| SCHEMBL904481 | 0.81 | SLC7A5 (0.42) | CYP1A2TAAR1MEN1KMT2ASLC7A5 | |
| SCHEMBL904480 | 0.81 | SLC7A5 (0.42) | CYP1A2TAAR1MEN1KMT2ASLC7A5 | |
| SCHEMBL1086155 | 0.80 | TAAR1 (0.53) | CTSCCYP1A2TAAR1SIGMAR1SLC18A2 | |
| SCHEMBL1310109 | 0.80 | TAAR1 (0.53) | CTSCCYP1A2TAAR1SIGMAR1SLC18A2 | |
| SCHEMBL1308687 | 0.80 | CTSC (0.42) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 | |
| SCHEMBL5031408 | 0.80 | CTSC (0.46) | CTSCEPHX1CYP1A2TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809650-A1 | SERINE PROTEASE INHIBITORS | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1997-12-03 | — | — | EP | disclosed |