SCHEMBL5031643

SCHEMBL5031643

NCCCN(N)CCCN

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.43
DNM1 Q05193 4/20 0.40
CA12 O43570 3/20 0.40
CA2 P00918 3/20 0.40
CA4 P22748 3/20 0.40
CA6 P23280 3/20 0.40
CA5A P35218 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CA5B Q9Y2D0 3/20 0.40
CA1 P00915 2/20 0.40
CA3 P07451 2/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.40
BLM P54132 1/20 0.40
CHRM2 P08172 1/20 0.38
TDP1 Q9NUW8 1/20 0.32
CASP2 P42575 2/20 0.30
MEN1 O00255 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446461 0.93
SCHEMBL13154479 0.85
SCHEMBL232231 0.85
SCHEMBL13154377 0.81
SCHEMBL991275 0.79 CA12 (0.55) CA12CA2CA4CA6CA5A
SCHEMBL15601439 0.76 CHRM2 (0.46) NFKB1DNM1CA12CA2CA4
SCHEMBL9020976 0.75
SCHEMBL23988567 0.74 DNM1 (0.50) NFKB1DNM1CA12CA2CA4
SCHEMBL15617010 0.74
SCHEMBL23663903 0.74 AOC3 (0.44) CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1924345-B1 PROCESS FOR CROSS-LINKING CELLULOSE ESTER MEMBRANES GE HEALTHCARE BIO SCIENCES AB (SE) 2014-10-29 EP disclosed
US-8496123-B2 Adding base to membrane comprising cellulose ester groups in presence of aqueous solution of bifunctional reagent under conditions which allow hydrolysis of ester groups to hydroxyl groups and crosslinking of hydroxyl groups with bifunctional reagent; hydrolysis and crosslinking occur simultaneously GE Healtcare Bio-Sciences AB (SE) 2013-07-30 US disclosed
US-20080179248-A1 Process for Cross-Linking Cellulose Ester Membranes GE HEALTHCARE BIO-SCIENCES AB (SE) 2008-07-31 US disclosed
EP-1924345-A2 PROCESS FOR CROSS-LINKING CELLULOSE ESTER MEMBRANES GE Healthcare Bio-Sciences AB (SE) 2008-05-28 EP disclosed
WO-2007017085-A2 PROCESS FOR CROSS-LINKING CELLULOSE ESTER MEMBRANES GE HEALTHCARE BIO-SCIENCES AB (SE) 2007-02-15 WO disclosed
US-5143999-A For sealing, adhesives, molding resins, casting resins or coating compositions CIBA-GEIGY CORPORATION (US) 1992-09-01 US disclosed