Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28753656 | 0.85 | MAPT (0.50) | CYP19A1CYP11B2CYP3A4CYP2D6LMNA | |
| SCHEMBL2785849 | 0.83 | CYP19A1 (0.49) | CYP19A1CYP11B2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28004787 | 0.76 | CYP19A1 (0.45) | CYP19A1CYP11B2NAPRTALDH1A1HTT | |
| SCHEMBL7559763 | 0.76 | NAPRT (0.44) | CYP19A1CYP11B2NAPRTALDH1A1HTT | |
| SCHEMBL7559764 | 0.76 | NAPRT (0.44) | CYP19A1CYP11B2NAPRTALDH1A1HTT | |
| SCHEMBL14346009 | 0.76 | NAPRT (0.44) | CYP19A1CYP11B2NAPRTALDH1A1HTT | |
| SCHEMBL13618861 | 0.74 | NAPRT (0.42) | NAPRTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL13141937 | 0.74 | CYP19A1 (0.72) | CYP19A1CYP11B2NAPRTALDH1A1MEN1 | |
| SCHEMBL6265077 | 0.72 | CYP19A1 (0.42) | CYP19A1CYP11B2NAPRTALDH1A1HTT | |
| SCHEMBL27684753 | 0.72 | HTT (0.57) | NAPRTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274419-A1 | Photoconductors | XEROX CORPORATION | 2008-11-06 | — | — | US | claimed |