Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702613 | 0.87 | CYP19A1 (0.61) | SLC6A2SLC6A4SLC6A3CYP19A1LMNA | |
| SCHEMBL30440878 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP3A4CYP19A1 | |
| SCHEMBL28711798 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CYP3A4LMNA | |
| SCHEMBL7349683 | 0.75 | CYP3A4 (0.41) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL3408213 | 0.75 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| Bromide SCHEMBL3812029 | 0.73 | CYP3A4 (0.41) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL246438 | 0.72 | KDM4E (0.53) | CYP3A4CYP2C19MAPTLMNAKDM4E | |
| SCHEMBL12333611 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL7810592 | 0.70 | — | — | |
| SCHEMBL28639731 | 0.70 | KDM4E (0.52) | CYP3A4CYP2C19MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274419-A1 | Photoconductors | XEROX CORPORATION | 2008-11-06 | — | — | US | claimed |