SCHEMBL5032081

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5029725	0.81	IL2 (0.56)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL5033771	0.81	IL2 (0.56)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL5030926	0.79	IL2 (0.53)	IL2NPC1RAB9ALMNADYRK1A
	SCHEMBL5027355	0.78	DYRK1A (0.45)	IL2NPC1RAB9ADYRK1ADYRK1B
	SCHEMBL4769462	0.77	IL2 (0.61)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL986898	0.77	NPC1 (0.50)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL986619	0.77	NPC1 (0.50)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL13640659	0.77	IL2 (0.51)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2305773	0.76	IL2 (0.54)	IL2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL2845664	0.76	IL2 (0.52)	IL2NPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.