Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031033 | 0.89 | LTA4H (0.40) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL1609518 | 0.81 | LTA4H (0.53) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5034225 | 0.81 | LTA4H (0.53) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5031012 | 0.81 | LTA4H (0.53) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5027548 | 0.81 | LTA4H (0.41) | LTA4HKCNH2KCNA3SMN1; SMN2ALDH1A1 | |
| SCHEMBL18108500 | 0.80 | LTA4H (0.43) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5801997 | 0.79 | LTA4H (0.50) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL3899078 | 0.77 | LTA4H (0.49) | LTA4HCYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL18108334 | 0.77 | LTA4H (0.42) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL18108315 | 0.77 | LTA4H (0.42) | LTA4HMLNRNR1I2ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999167-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | Novolen Technology Holdings, C.V. (NL) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106348-A2 | ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-09-20 | — | — | WO | disclosed |
| US-20070213204-A1 | Ziegler-Natta catalyst with in situ-generated donor | NOVOLEN TECHNOLOGY HOLDINGS C.V. | 2007-09-13 | — | — | US | disclosed |