SCHEMBL503227

SCHEMBL503227

Nc1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 8/20 1.00
NFE2L2 Q16236 7/20 1.00
CRHBP P24387 1/20 1.00
CRHR2 Q13324 1/20 1.00
KMT2A Q03164 7/20 0.62
USP2 O75604 6/20 0.62
MEN1 O00255 6/20 0.62
MAPT P10636 4/20 0.62
CYP3A4 P08684 3/20 0.62
CASP1 P29466 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
RGS12 O14924 1/20 0.62
CYP1A2 P05177 1/20 0.62
POLB P06746 1/20 0.62
PARP1 P09874 1/20 0.62
THRB P10828 1/20 0.62
CYP2C9 P11712 1/20 0.62
APEX1 P27695 1/20 0.62
BRCA1 P38398 1/20 0.62
MTOR P42345 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16582580 0.88 KEAP1 (0.78) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL10015438 0.84 KEAP1 (0.70) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL15709366 0.83 KEAP1 (0.70) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL29416695 0.83 KEAP1 (0.70) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL10015441 0.82 KEAP1 (0.68) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL12874092 0.82 KEAP1 (0.69) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL10015445 0.80 KEAP1 (0.66) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL14461125 0.80 KEAP1 (0.66) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL10015446 0.80 KEAP1 (0.64) KEAP1NFE2L2CRHBPCRHR2KMT2A
SCHEMBL30516566 0.79 USP2 (0.65) KEAP1NFE2L2CRHBPCRHR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650876-B 2- (fluoranthene-3-iminomethyl) -phenol, preparation method thereof, bamboo shoot and bamboo fiber detection test paper prepared from same and application thereof 国家林业和草原局竹子研究开发中心 2023-12-12 CN claimed
CN-115650876-A 2- (fluoranthene-3-imine methyl) -phenol, preparation method thereof, bamboo shoot fiber detection test paper prepared from phenol, and application of bamboo shoot fiber detection test paper 国家林业和草原局竹子研究开发中心 2023-01-31 CN claimed
CN-104530266-B The polymer of imidizate comprising luminophore and their method of acquisition 艾尼股份公司 2017-12-08 CN claimed
EP-2358765-A1 IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM ENI S.p.A. (IT) 2011-08-24 EP claimed
WO-2010078933-A1 IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM ENI S.P.A. (IT) 2010-07-15 WO claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-6686206-B2 DETECTION OF BASIC GASES AND OTHERS PARTICLES IN GASES OR LIQUIDS; OBTAIN SAMPLE, INCUBATE WITH FLUORESCENT DYES, ACTIVATE DYES, MONITOR SIGNAL AND ANALYZE RESPONSE ALTAIR CENTER, LLC 2004-02-03 US claimed
US-5378896-A Harmful solar radiation detection device KNJASCHEWITSCH SASCHA R (CA) 1995-01-03 US claimed
US-5298197-A Chemiluminescent microemulsions THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1994-03-29 US claimed
US-4729950-A AROMATIC AMINE, PEROXIDASE, OXIDIZER, 2,3-DIHYDRO-1,4-PHTHALAZINEDIONE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1988-03-08 US claimed
JP-63063654-A None JP disclosed
CN-119931031-A White light nylon copolymer and preparation method and application thereof 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-117865878-A Chiral indoline-3-one derivative and preparation method thereof 郑州大学 2024-04-12 CN disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
CN-115650876-B 2- (fluoranthene-3-iminomethyl) -phenol, preparation method thereof, bamboo shoot and bamboo fiber detection test paper prepared from same and application thereof 国家林业和草原局竹子研究开发中心 2023-12-12 CN disclosed
WO-1991002040-A1 CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-02-21 WO disclosed
US-4777108-A Transfer imaging system THE MEAD CORPORATION (US) 1988-10-11 US disclosed
JP-S6363654-A FLUORANTHENE-3-ISOTHIOCYANATE AND FLUORESCENT LABELING REAGENT COMPOSED OF SAID COMPOUND JAPAN TOBACCO INC 1988-03-22 JP disclosed
US-4729950-A AROMATIC AMINE, PEROXIDASE, OXIDIZER, 2,3-DIHYDRO-1,4-PHTHALAZINEDIONE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1988-03-08 US disclosed
US-4097488-A PROTEINS, NUCLEIC ACIDS TEIKA SEIYAKU KABUSHIKI KAISHA (JA) 1978-06-27 US disclosed