⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541990 | 0.97 | — | — | |
| SCHEMBL27941587 | 0.97 | HCAR2 (0.56) | — | |
| Water SCHEMBL27583249 | 0.97 | HCAR2 (0.56) | — | |
| SCHEMBL28147137 | 0.97 | HCAR2 (0.56) | — | |
| Hydrochloric Acid SCHEMBL12971394 | 0.97 | HCAR2 (0.56) | — | |
| Hydrochloric Acid SCHEMBL25242562 | 0.97 | HCAR2 (0.56) | — | |
| Hydrochloric Acid SCHEMBL28749975 | 0.95 | HCAR2 (0.54) | — | |
| Sulfuric Acid SCHEMBL27952916 | 0.91 | HCAR2 (0.50) | — | |
| Formic Acid SCHEMBL25244373 | 0.91 | HCAR2 (0.50) | — | |
| SCHEMBL27941661 | 0.87 | HCAR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034535-B1 | AZA-QUINOLINE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2026-03-04 | — | — | EP | claimed |
| EP-3350313-B1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) | 2025-11-26 | — | — | EP | claimed |
| WO-2025224759-A1 | INDANOL SUBSTITUTED DIAMINO PYRIMIDINE CARBOXAMIDES AS DUAL ATM/DNA-PK INHIBITORS | BUGWORKS RESEARCH INDIA PVT. LTD (IN) | 2025-10-30 | — | — | WO | claimed |
| EP-3455204-B1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | Jubilant Epicore LLC (US) | 2025-10-29 | — | — | EP | claimed |
| EP-3941916-B1 | PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, AND USES RELATED THERETO | UNIV EMORY (US) | 2025-10-01 | — | — | EP | claimed |
| US-20250230154-A1 | COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2025-07-17 | — | — | US | claimed |
| EP-4532014-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Cerevance, Inc. (US) | 2025-04-09 | — | — | EP | claimed |
| CN-119306708-A | FLT3-HDAC double-target inhibitor and preparation method and application thereof | 山东大学 | 2025-01-14 | — | — | CN | claimed |
| CN-113727972-B | Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof | 韩国科学技术研究院 | 2024-12-27 | — | — | CN | claimed |
| WO-2024233951-A1 | HETEROCYCLIC COMPOUNDS FOR IMAGING AGGREGATED ALPHA SYNUCLEIN IN THE SYNUCLEINOPATHIES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-11-14 | — | — | WO | claimed |
| WO-2001038308-A1 | NOVEL 5-PYRIMIDINECARBOXAMIDE DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD (KR) | 2001-05-31 | — | — | WO | claimed |
| EP-1054004-A1 | NOVEL PYRIMIDINE-5-CARBOXAMIDE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-11-22 | — | — | EP | claimed |
| CN-1014990-B | Process for the preparation of 5-pyrimidinecarboxamides derivatives | UNIROYAL CHEM CO INC (US) | 1991-12-04 | — | — | CN | claimed |
| CN-1014991-B | PURIFICATION OF 5-PYRIMIDINECARBOXAMIDES | UNIROYAL LTD (CA) | 1991-12-04 | — | — | CN | claimed |
| CN-1038450-A | The 5-pyrimidine carboxamide analog derivative that replaces | UNIROYAL CHEM CO INC (US) | 1990-01-03 | — | — | CN | claimed |
| US-4845217-A | FORMING AN ABDUCT WITH AN ORGANIC BASE | UNIROYAL CHEMICAL LTD./LTEE (CA) | 1989-07-04 | — | — | US | claimed |
| US-4636508-A | 5-pyrimidinecarboxyamides and treatment of leukemia therewith | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-01-13 | — | — | US | claimed |
| CN-86102767-A | The preparation method of 5-pyrimidine carboxamide analog derivative | — | 1987-01-07 | — | — | CN | claimed |
| CN-86103314-A | The purification of 5-pyrimidinecarboxamides | — | 1986-12-17 | — | — | CN | claimed |
| EP-0202823-A2 | Purification of 5-pyrimidinecarboxamides | UNIROYAL LIMITED (CA) | 1986-11-26 | — | — | EP | claimed |