Urea

Urea

SCHEMBL5032730

CC(CO)=C(O)CO.NC(N)=O

nearest known ligand 0.37

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
OR51E2 Q9H255 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ACHE P22303 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28844232 0.85
SCHEMBL18791723 0.70
Glycolic Acid SCHEMBL27899251 0.69
SCHEMBL8912105 0.69
Urea SCHEMBL5032726 0.69 LMNA (0.39) LMNAALOX15BLMPMP22OR51E2
SCHEMBL8912100 0.69
Glycolic Acid SCHEMBL27867705 0.68
Acetic Acid SCHEMBL30298819 0.67 FFAR3 (0.70) LMNAALOX15BLMPMP22OR51E2
Acetic Acid SCHEMBL875913 0.67
Acetic Acid SCHEMBL27616022 0.67 FFAR3 (0.70) LMNAALOX15BLMPMP22OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080187735-A1 Non-Woven Fabric and Food Casing Which is Produced Therefrom and Which is Based on Cellulose Hydrate KALLE GMBH (DE) 2008-08-07 US disclosed
EP-1811852-A1 NON-WOVEN FABRIC AND FOOD CASING WHICH IS PRODUCED THEREFROM AND WHICH IS BASED ON CELLULOSE HYDRATE Kalle GmbH (DE) 2007-08-01 EP disclosed
WO-2006048235-A1 NON-WOVEN FABRIC AND FOOD CASING WHICH IS PRODUCED THEREFROM AND WHICH IS BASED ON CELLULOSE HYDRATE KALLE GMBH (DE) 2006-05-11 WO disclosed
US-RE30227-E Agent for brightening and removing greyness from textiles CIBA-GEIGY CORPORATION (US) 1980-03-11 US disclosed
US-4008172-A Agent for brightening and removing greyness from textiles CIBA-GEIGY CORPORATION (US) 1977-02-15 US disclosed