Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583837 | 0.92 | L3MBTL1 (0.38) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5539051 | 0.92 | CNR2 (0.42) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL4583844 | 0.91 | L3MBTL1 (0.38) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5540948 | 0.90 | L3MBTL1 (0.39) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5545334 | 0.90 | L3MBTL1 (0.42) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5128863 | 0.89 | L3MBTL1 (0.40) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5132965 | 0.89 | L3MBTL1 (0.40) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL15163546 | 0.88 | L3MBTL1 (0.42) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5540820 | 0.88 | L3MBTL1 (0.41) | CNR2L3MBTL1MEN1KMT2AHTT | |
| SCHEMBL5545426 | 0.86 | L3MBTL1 (0.42) | CNR2L3MBTL1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910355-A2 | HIV INTEGRASE INHIBITORS | SmithKline Beecham Corporation (US) | 2008-04-16 | — | — | EP | claimed |
| WO-2007019100-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-15 | — | — | WO | claimed |
| EP-1910355-A2 | HIV INTEGRASE INHIBITORS | SmithKline Beecham Corporation (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007019100-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-15 | — | — | WO | disclosed |