Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034526 | 0.94 | PPARA (0.47) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5037102 | 0.90 | CYP1A2 (0.45) | PPARALMNAMAPTNPC1HPGD | |
| SCHEMBL5037057 | 0.87 | PPARA (0.39) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5031956 | 0.86 | PPARA (0.49) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5031926 | 0.83 | PPARA (0.44) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5032938 | 0.79 | PPARA (0.49) | PPARALMNAMAPTPPARDNPC1 | |
| SCHEMBL3418656 | 0.79 | KDM4E (0.58) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5034523 | 0.78 | HPGD (0.46) | PPARAMAPTPPARGNPC1HPGD | |
| SCHEMBL3419218 | 0.77 | PPARA (0.51) | PPARALMNAMAPTPPARDPPARG | |
| SCHEMBL5034527 | 0.77 | PPARA (0.47) | PPARALMNAMAPTPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |