Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034526 | 0.86 | PPARA (0.47) | PPARAPPARDGAASMN1; SMN2CHRM4 | |
| SCHEMBL5032982 | 0.82 | PPARA (0.49) | PPARAPPARDGAASMN1; SMN2CHRM4 | |
| SCHEMBL5032867 | 0.79 | PPARA (0.44) | PPARAPPARDGAALMNAMAPT | |
| SCHEMBL5037057 | 0.78 | PPARA (0.39) | PPARAPPARDLMNAMAPTKDM4E | |
| SCHEMBL5031870 | 0.77 | LMNA (0.43) | GAASMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL5037102 | 0.76 | CYP1A2 (0.45) | PPARASMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL5037183 | 0.75 | NPC1 (0.45) | PPARAPPARDGAASMN1; SMN2MAPT | |
| SCHEMBL5030063 | 0.75 | CHRM3 (0.42) | RAB9ANPC1POLBHPGD | |
| SCHEMBL13541886 | 0.74 | MAOB (0.58) | PPARAPPARDGAASMN1; SMN2CHRM4 | |
| SCHEMBL5034446 | 0.73 | SCD (0.41) | PPARAPPARDCHRM4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |