Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.68 |
| ▸ | PPARD | Q03181 | 12/20 | 0.68 |
| ▸ | PPARG | P37231 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426198 | 0.86 | PPARA (0.62) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL5032977 | 0.85 | PPARA (0.61) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL6502631 | 0.79 | PPARA (0.75) | PPARAPPARDPPARG | |
| SCHEMBL3418796 | 0.78 | PPARD (0.63) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL6504915 | 0.78 | PPARG (0.75) | PPARAPPARDPPARG | |
| SCHEMBL3416652 | 0.77 | PPARD (0.68) | PPARAPPARDPPARGTRPV1MCHR1 | |
| SCHEMBL13460925 | 0.76 | PPARG (0.60) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL5031740 | 0.74 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL6427520 | 0.70 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL5031956 | 0.70 | PPARA (0.49) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20050014833-A1 | Cyclic compound and ppar agonist | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452521-A1 | CYCLIC COMPOUND AND PPAR AGONIST | Eisai Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014833-A1 | Cyclic compound and ppar agonist | PPARA, PPARG, PPARD | PPARA 1/4885PPARD 3/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.