Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.61 |
| ▸ | PPARD | Q03181 | 12/20 | 0.61 |
| ▸ | PPARG | P37231 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032986 | 0.85 | PPARA (0.68) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL5034465 | 0.85 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL6426198 | 0.83 | PPARA (0.62) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL5032979 | 0.79 | PDE4A (0.42) | PPARAPPARDPPARG | |
| SCHEMBL5031908 | 0.77 | PPARA (0.41) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL5032817 | 0.77 | PPARD (0.47) | PPARAPPARDPPARG | |
| SCHEMBL5034466 | 0.77 | HTT (0.43) | PPARAPPARDPPARGKMT2A | |
| SCHEMBL5034503 | 0.76 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5029970 | 0.75 | PPARA (0.44) | PPARAPPARDPPARGKMT2A | |
| SCHEMBL6502631 | 0.75 | PPARA (0.75) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371777-B2 | Cyclic compound and PPAR agonist | EISAI CO., LTD. (JP) | 2008-05-13 | — | — | US | disclosed |