SCHEMBL503312

SCHEMBL503312

N[C@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.61
PTGS1 P23219 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
PTPRA P18433 1/20 0.53
MMP2 P08253 2/20 0.52
MC4R P32245 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
HIF1A Q16665 2/20 0.51
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ALOX15 P16050 1/20 0.51
HTR2A P28223 1/20 0.51
PTGS2 P35354 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26443 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL437181 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL26444 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL4754409 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL22285084 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL7729304 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL2724117 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL4754408 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL8721103 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL8716271 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240350681-A1 RADIOLABELED MELANOCORTIN 1 RECEPTOR-SPECIFIC ALPHA-MELANOCYTE-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-10-24 US claimed
EP-4444740-A2 P53 PEPTIDOMIMETIC MACROCYCLES Merck Sharp & Dohme LLC (US) 2024-10-16 EP claimed
CN-118496313-A Calcium sensitive receptor agonist compounds and uses thereof 北京拓界生物医药科技有限公司 2024-08-16 CN claimed
US-11992537-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2024-05-28 US claimed
WO-2023107353-A2 P53 PEPTIDOMIMETIC MACROCYCLES MERCK SHARP & DOHME LLC (US) 2023-06-15 WO claimed
EP-4175970-A1 PEPTIDES AND USES THEREOF Preveceutical Medical Inc. (CA) 2023-05-10 EP claimed
CN-115851645-A Proteobacterium vulgaris meso-diaminopimelate dehydrogenase mutant and application thereof 江南大学 2023-03-28 CN claimed
US-20230041996-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF BEIJING TUO JIE BIOPHARMACEUTICAL CO. LTD. (CN) 2023-02-09 US claimed
EP-4091623-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2022-11-23 EP claimed
WO-2022000043-A1 PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2022-01-06 WO claimed
US-20160022636-A1 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2016-01-28 US claimed
EP-2968240-A2 PHYSIOLOGICAL LIGANDS FOR GPR139 Janssen Pharmaceutica, N.V. (BE) 2016-01-20 EP claimed
US-20140336216-A1 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2014-11-13 US claimed
WO-2014152917-A2 PHYSIOLOGICAL LIGANDS FOR GPR139 JANSSEN PHARMACEUTICA NV (BE) 2014-09-25 WO claimed
US-20080233137-A1 Compounds that Block the C5a Receptor and Their Use in Therapy ALLIGATOR BIOSCIENCE AB (SE) 2008-09-25 US claimed
CN-1997664-A Compounds that block the C5A receptor and their use in therapy ALLIGATOR BIOSCIENCE AB PUBL (SE) 2007-07-11 CN claimed
EP-1586583-A2 Compounds that block C5a complement receptor and their use in therapy Alligator Bioscience AB (publ) (SE) 2005-10-19 EP claimed
WO-2003006048-A1 COMBINATION OF CHIPS (CHEMOTAXIS INHIBITING PROTEIN FROM STAPHYLOCOCCUS AUREUS)-BASED COMPOUNDS JARI PHARMACEUTICALS B.V. (NL) 2003-01-23 WO claimed
EP-1025127-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES Wapharm AB (SE) 2000-08-09 EP claimed
WO-1998037097-A1 MSH-RECEPTOR SUBTYPE SELECTIVE CYCLIC PEPTIDES WAPHARM AB (SE) 1998-08-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992537-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy MC1R, MC5R, MC3R SLC7A5 200/4885PTGS1 3324/4885ALPI 2447/4885
US-20240350681-A1 RADIOLABELED MELANOCORTIN 1 RECEPTOR-SPECIFIC ALPHA-MELANOCYTE-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY MC1R, MC3R, MC5R SLC7A5 196/4885PTGS1 3218/4885ALPI 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.