SCHEMBL437181

SCHEMBL437181

N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O.N[C@@H](Cc1ccc([N+](=O)[O-])cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.61
PTGS1 P23219 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
PTPRA P18433 1/20 0.53
MMP2 P08253 2/20 0.52
MC4R P32245 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.52
HIF1A Q16665 2/20 0.51
KDM4E B2RXH2 1/20 0.51
USP2 O75604 1/20 0.51
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ALOX15 P16050 1/20 0.51
HTR2A P28223 1/20 0.51
PTGS2 P35354 1/20 0.51
RECQL P46063 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26443 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL503312 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL26444 1.00 SLC7A5 (0.61) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL4754409 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL22285084 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL7729304 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL2724117 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL4754408 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Water SCHEMBL8721103 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP
Hydrochloric Acid SCHEMBL8716271 0.98 SLC7A5 (0.59) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1781310-B1 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME UNIV RAMOT (IL) 2015-10-14 EP claimed
US-8927689-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-01-06 US claimed
US-8796023-B2 Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-08-05 US claimed
US-20120063276-A1 PEPTIDE NANOSTRUCTURES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2012-03-15 US claimed
US-8017586-B2 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-09-13 US claimed
US-7786086-B2 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2010-08-31 US claimed
EP-1781310-A4 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME UNIV RAMOT (IL) 2009-07-08 EP claimed
US-20090123553-A1 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-05-14 US claimed
US-20090121709-A1 Peptide nanostructures encapsulating A foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-05-14 US claimed
US-7504383-B2 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2009-03-17 US claimed
US-7491699-B2 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. 2009-02-17 US claimed
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2008-01-10 US claimed
EP-1781310-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME Ramot at Tel Aviv University Ltd. (IL) 2007-05-09 EP claimed
US-20060079455-A1 Peptide nanostructures encapsulating a foreign material and method of manufacturing same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 US claimed
US-20060079454-A1 Peptide nanostructures and methods of generating and using the same RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-04-13 US claimed
WO-2006027780-A2 PEPTIDE NANOSTRUCTURES CONTAINING END-CAPPING MODIFIED PEPTIDES AND METHODS OF GENERATING AND USING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-03-16 WO claimed
WO-2006013552-A2 ARTICLES OF PEPTIDE NANOSTRUCTURES AND METHOD OF FORMING THE SAME RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-02-09 WO claimed
US-20240167062-A1 HYDROGEL SYSTEM FOR CONTROLLING OXYGEN CONCENTRATION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-05-23 US disclosed
EP-1144368-A2 ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS American Cyanamid Company (US) 2001-10-17 EP disclosed
WO-2000044709-A2 ACETYLENIC α-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240167062-A1 HYDROGEL SYSTEM FOR CONTROLLING OXYGEN CONCENTRATION HIF1A, HAO2, EGLN2 SLC7A5 346/4885PTGS1 55/4885ALPI 4725/4885
US-20080009434-A1 at least one aromatic amino acid (phenylalanine); hollow and fibrillar peptide; macroscopic and microscopic articles; self-assembled; 9-fluorenylmethyloxycarbonyl (Fmoc) and benzyloxycarbonyl (Cbz); slow release of drug, nucleic acid molecule or a polypeptide; antibody DNPEP, LNPEP, ANPEP SLC7A5 17/4885PTGS1 4835/4885ALPI 2343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.